Help reduce preventable stillbirths by informing and empowering parents about the latest’s health advancements before during and after pregnancy. We believe that advancement in antenatal screening with MRI can lead to a better understanding/prevention of stillbirth and assist in the prevention of umbilical cord accidents thus reducing stillbirth and brain damage.
POAC Also advocates for pediatric and adult cancer research, alternative treatments and immunotherapy in collaboration with Prof. Dr Martin Grootveld of DeMontfort University in Leicester and Prof. Dr. Dana Flavin who are leading new research focused on enhancing the body’s natural ability to fight cancer. Brain Tumours the most common cancer occurring among those aged 0-14, and the leading cause of cancer-related deaths in children (males and females) aged 0-14, according to a 2016 report that places brain tumours in children above leukemia for both statistics.
POAC Will work and develop a much needed epidemiology study, understanding environmental and genetic risk factors by gathering information from parents whose children have suffered this horrible brain disease. Parents together could have the key to unlock very important information to understand the origin and cause of Pediatric Brain Tumours.
Children with DIPG continue to suffer from little to no clinical improvement in overall outcome despite the significant number of clinical trials generated to date. The persisting standard of care is radiation, which is palliative in nature, and then a consideration of various single drug administrations or radiation + clinical trial.
There has been a significant reticence to treat children with DIPG with a multimodal and multi drug approach despite the almost universally inevitable decline and death of these children on single drug treatments. Parents equally continue to choose the same pathway to a continually morbid outcome.
POAC is honoured to welcome
Prof. Mauro Tognon
Head of the Experimental Biology Laboratories, Department of Morphology, Surgery and Experimental Medicine. Prof. Tognon is member of the European Academy of Tumour Immunology and is based at University of Ferrara Ferrara Italy. Research - Specific Antibodies Reacting with SV40 LargeT Antigen Mimotopes in Serum Samples of Healthy Subjects. Why are Doctors not going after the root cause of cancer "and it’s a tragedy".
Adobe Acrobat document [472.9 KB]
Mark Humphries Request for Sponsorship
Increasing the availability of new cancer therapies. Alternative treatments in the field of immunotherapy have been available to patients in other countries for some years but are generally unavailable to patients in the UK.
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The 2016 World Health Organization Classification of Tumors of the Central Nervous System
Pediatric diffuse gliomas:
In the past, pediatric diffuse gliomas were grouped with their adult counterparts, despite known differences in behavior
between pediatric and adult gliomas with similar histological appearances. Information on the distinct underlying genetic abnormalities in pediatric diffuse gliomas is beginning to allow the
separation of some entities from histologically similar adult counterparts [24, 37, 52].One narrowly defined group of tumors primarily occurring in children (but sometimes in adults too) is
characterized by K27M mutations in the histone H3 gene H3F3A, or less commonly in the related HIST1H3B gene, a diffuse growth pattern, and a midline location (e.g., thalamus, brain stem, and spinal
cord) (Fig. 4) [19, 51]. "This newly defined entity
is termed diffuse midline glioma", H3 K27M–mutant and includes tumors previously
referred to as diffuse intrinsic pontine glioma (DIPG). The identification of this phenotypically and molecularly defined set of tumors provides a rationale for therapies directed against the effects
of these mutations.
Read more click on PDF:
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POAC Epidemiology Study
POAC in collaboration with Prof Dr Dana Flavin (Collmed) is now working on a Peadiatric Brain cancer Epidemiology study. POAC questionnaire is in progress and will soon be available to Parents and carers wishing to take part.
Project Alive & Kicking USA
POAC, would like to thank Mr Steven Holmes for his kind donation of 250Uk pounds from his latest cycle run along the banks of the river Rhine Germany. “Well done”
Reduced Fetal Movements (RFM) Guidelines Royal College of Obstetricians &Gynaecologists
click here for more information.
POAC - E-Brochure on Umbilical Cord Accidents Prevention 2012
Click here to view and or download the E-brochure
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Monica Health Care Products UK.
Monica world leading in maternal and fetal monitoring systems have offered their full support to POAC. At Monica our aims and values are closely aligned to POAC and through the advancement of technology and education of the clinicians and carers involved we aim to reduce stillbirths, unnecessary interventions and improve outcomes for mothers, children and families as a whole. We wish POAC every success in their endeavours. Further information on Fetal monitoring see articles. For further information visit www.monicahealthcare.com
at 40 weekswould ‘improve the survival rate’
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founder of elective caesarean & Fully supports POAC
Pauline says POAC deserves recognition for its commitment to exploring new research and helping prevent the loss of precious lives. Technology is often seen as a last resort in pregnancy and childbirth, and the tendency is to approach intervention as a last resort only. In fact, using technology during pregnancy could help many women to make a more informed choice about their birth plan, in consultation with a medical professional.
Delivering better ways of preventing stillbirths
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POAC is an official charity with OSCR registration, click here for more INFO.